A few years ago I used to shoot the 500 S&W Mag in a Thompson Center Encore rifle. I played with all kinds of bullets and powders. It was a lot of fun. The 500 S&W is a great cartridge with power to take the largest game on Earth including buffalo and elephant. Cast bullets make the 500 S&W really exciting. I shot cast bullets ranging from 300 grains to 700 grains.
Here are some of the loads I shot. The one on the far left is the 700 grain WFNGC. The max load will push it to 1340 fps from a 6″ barrel. The center round is the 600 grain LFNGC and will go about 1500 fps. The small one on the far right is the 440 grain FNGC. The 440 grain will do about 1750 fps.